An Air India Boeing 787 Dreamliner crashed shortly after takeoff from Ahmedabad on Thursday, killing dozens and injuring many in a residential area near the airport.

The aircraft, bound for London’s Gatwick Airport with 242 passengers and crew onboard, struck a medical college hostel, causing significant damage, according to Reuters.

The 787 Dreamliner, a flagship wide-body jet designed for long-haul routes, was delivered to Air India in 2014, according to FlightRadar24 data.

The incident marks a rare failure for the popular aircraft, which has been a cornerstone of Boeing’s commercial portfolio.

The cause of the crash remains unclear, with investigations expected to take months.

Under international aviation protocols, India will lead the probe, collaborating with Boeing, engine manufacturers, and other stakeholders. The tragedy is likely to intensify scrutiny on Air India’s safety protocols and Boeing’s aircraft reliability.

The crash sent ripples through the aviation industry, with Air India’s stock and Boeing’s shares expected to face pressure in trading sessions.

Authorities have not released further details on casualties or the extent of ground damage as rescue operations continue.

Initial flight-path data “shows that the aircraft reached a maximum barometric altitude of 625 feet (airport altitude is about 200 feet) and then it started to descend with an vertical speed of -475 feet per minute,” FlightRadar said on X.

Boeing stated “We are in contact with Air India regarding Flight 171 and stand ready to support them.

 “Our thoughts are with the passengers, crew, first responders and all affected.”

The plane was powered by two GE Aerospace engines.

“We extend our heartfelt sympathies to the families and loved ones of those impacted,” a GE spokesperson said. “We have activated our emergency response team, and we are prepared to support our customer and the investigation.”

The U.S. National Transportation Safety Board announced it will dispatch a team of investigators to India.

The incident took place shortly before the high-profile Paris Air Show, scheduled for next week, where both Boeing and its rival Airbus are expected to unveil hundreds of aircraft orders.